diff --git a/java-vertexai/google-cloud-vertexai/src/main/java/com/google/cloud/vertexai/VertexAI.java b/java-vertexai/google-cloud-vertexai/src/main/java/com/google/cloud/vertexai/VertexAI.java
index 8284e5821d88..500d902e3089 100644
--- a/java-vertexai/google-cloud-vertexai/src/main/java/com/google/cloud/vertexai/VertexAI.java
+++ b/java-vertexai/google-cloud-vertexai/src/main/java/com/google/cloud/vertexai/VertexAI.java
@@ -166,8 +166,15 @@ private VertexAI(
     this.llmClientSupplier =
         Suppliers.memoize(llmClientSupplierOpt.orElse(this::newLlmUtilityClient));
 
-    this.apiEndpoint =
-        apiEndpoint.orElse(String.format("%s-aiplatform.googleapis.com", this.location));
+    if (apiEndpoint.isPresent()) {
+      this.apiEndpoint = apiEndpoint.get();
+    } else {
+      if ("global".equals(this.location)) {
+        this.apiEndpoint = "aiplatform.googleapis.com";
+      } else {
+        this.apiEndpoint = String.format("%s-aiplatform.googleapis.com", this.location);
+      }
+    }
   }
 
   /** Builder for {@link VertexAI}. */
diff --git a/java-vertexai/google-cloud-vertexai/src/test/java/com/google/cloud/vertexai/VertexAITest.java b/java-vertexai/google-cloud-vertexai/src/test/java/com/google/cloud/vertexai/VertexAITest.java
index 58a20773dc30..3d005dc1feb0 100644
--- a/java-vertexai/google-cloud-vertexai/src/test/java/com/google/cloud/vertexai/VertexAITest.java
+++ b/java-vertexai/google-cloud-vertexai/src/test/java/com/google/cloud/vertexai/VertexAITest.java
@@ -48,7 +48,9 @@
 public final class VertexAITest {
   private static final String TEST_PROJECT = "test_project";
   private static final String TEST_LOCATION = "test_location";
+  private static final String GLOBAL_LOCATION = "global";
   private static final String TEST_ENDPOINT = "test_endpoint";
+  private static final String GLOBAL_ENDPOINT = "aiplatform.googleapis.com";
   private static final String TEST_DEFAULT_ENDPOINT =
       String.format("%s-aiplatform.googleapis.com", TEST_LOCATION);
   private static final Optional<String> EMPTY_ENV_VAR_OPTIONAL = Optional.ofNullable(null);
@@ -344,6 +346,27 @@ public void testInstantiateVertexAI_builderLocationFromCLOUD_ML_REGION_shouldCon
     }
   }
 
+  @Test
+  public void testInstantiateVertexAI_builderLocationFromGLOBAL_REGION_shouldContainRightFields() {
+    try (MockedStatic mockedStaticVertexAI = mockStatic(VertexAI.class)) {
+      mockedStaticVertexAI
+          .when(() -> VertexAI.getEnvironmentVariable("GOOGLE_CLOUD_REGION"))
+          .thenReturn(Optional.of(GLOBAL_LOCATION));
+      mockedStaticVertexAI
+          .when(() -> VertexAI.getEnvironmentVariable("CLOUD_ML_REGION"))
+          .thenReturn(Optional.empty());
+      mockedStaticVertexAI
+          .when(() -> VertexAI.getEnvironmentVariable("GOOGLE_CLOUD_PROJECT"))
+          .thenReturn(Optional.of(TEST_PROJECT));
+
+      vertexAi = new VertexAI.Builder().build();
+
+      assertThat(vertexAi.getProjectId()).isEqualTo(TEST_PROJECT);
+      assertThat(vertexAi.getLocation()).isEqualTo(GLOBAL_LOCATION);
+      assertThat(vertexAi.getApiEndpoint()).isEqualTo(GLOBAL_ENDPOINT);
+    }
+  }
+
   @Test
   public void testInstantiateVertexAI_builderWithScopes_throwsIlegalArgumentException()
       throws IllegalArgumentException {